| Bioactivity | CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity[1]. |
| Invitro | HIV-1 entry is triggered by interaction of gp120 with CD4 and chemokine receptors (CKRs), such as CCR5 and CXCR4[1]. |
| Name | CXCR4 antagonist 1 |
| CAS | 675135-69-0 |
| Formula | C27H43N7 |
| Molar Mass | 465.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yuta Hikichi, et al. Increased HIV-1 Sensitivity to Neutralizing Antibodies by Mutations in the Env V3-coding Region for Resistance to CXCR4 Antagonists. J Gen Virol. 2016 Sep;97(9):2427-2440. |