Bioactivity | CX-5461 (Standard) is the analytical standard of CX-5461. This product is intended for research and analytical applications. CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively. |
CAS | 1138549-36-6 |
Formula | C₂₇H₂₇N₇O₂S |
Molar Mass | 513.61 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |