PeptideDB

CX-5011

CAS: 1333382-30-1 F: C20H11N4NaO2 W: 362.32

CX-5011 is a CK2 inhibitor. CX-5011 also induces Rac1 activation. CX-5011 induces apoptosis and induces cancer cell deat
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Bioactivity CX-5011 is a CK2 inhibitor. CX-5011 also induces Rac1 activation. CX-5011 induces apoptosis and induces cancer cell death[1][2].
Name CX-5011
CAS 1333382-30-1
Formula C20H11N4NaO2
Molar Mass 362.32
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. D'Amore C, et al. "Janus" efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms. Biochim Biophys Acta Mol Cell Res. 2020 Nov;1867(11):118807. [2]. Salizzato V, et al. Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies. Oncotarget. 2016 Apr 5;7(14):18204-18.