Bioactivity | CW-3308 is an orally effective PROTAC targeting BRD9. CW-3308 consists of PROTAC target protein ligand Naphthyridin-Me-dimethoxybenzene-COOH (HY-159596), Linker 3-Azaspiro[5.5]undecane-9-methanol (HY-159598), and E3 ubiquitin ligase ligand Thalidomide-methylpyrrolidine (HY-159597), of which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-pyrrolidine-C-azaspiro (HY-159599)[1]. |
Target | BRD9 |
Formula | C45H48N6O8 |
Molar Mass | 800.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |