| Bioactivity | CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1]. | ||||||||||||
| Invitro | CVT-11127 (1 µM, 48 h) shows antiproliferation activity in H460 cells[1].CVT-11127 (1 µM, 48 h) decreases the the population of cells in S-phase by 75%[1].CVT-11127 (1 µM, 48 h) induces apoposis in H460 cells[1].CVT-11127 (1, 2 µM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells[1]. Cell Proliferation Assay[1] Cell Line: | ||||||||||||
| Name | CVT-11127 | ||||||||||||
| CAS | 1018674-83-3 | ||||||||||||
| Formula | C25H23Cl2N5O3 | ||||||||||||
| Molar Mass | 512.39 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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