PeptideDB

CVT-11127

CAS: 1018674-83-3 F: C25H23Cl2N5O3 W: 512.39

CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127
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Bioactivity CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1].
Invitro CVT-11127 (1 µM, 48 h) shows antiproliferation activity in H460 cells[1].CVT-11127 (1 µM, 48 h) decreases the the population of cells in S-phase by 75%[1].CVT-11127 (1 µM, 48 h) induces apoposis in H460 cells[1].CVT-11127 (1, 2 µM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells[1]. Cell Proliferation Assay[1] Cell Line:
Name CVT-11127
CAS 1018674-83-3
Formula C25H23Cl2N5O3
Molar Mass 512.39
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month