| Bioactivity | CU-76 is an inhibitor for human cyclic GMP-AMP synthase (hcGAS) with an IC50 of 0.24 μM. CU-76 selectively inhibits the DNA pathway in human cells, and can be used in autoimmune research[1]. |
| CAS | 2400954-58-5 |
| Formula | C11H8F2IN5O2 |
| Molar Mass | 407.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Padilla-Salinas R, et al., Discovery of Small-Molecule Cyclic GMP-AMP Synthase Inhibitors. J Org Chem. 2020 Feb 7;85(3):1579-1600. |