| Bioactivity | CTOP is a potent and highly selective μ-opioid receptor antagonist. CTOP antagonizes the acute morphine-induced analgesic effect and hypermotility. CTOP enhances extracellular dopamine levels in the nucleus accumbens. CTOP dose-dependently enhances locomotor activity[1][2]. |
| Name | CTOP |
| CAS | 103429-31-8 |
| Sequence | Phe-Cys-Tyr-Trp-{Orn}-Thr-{Pen}-Thr-NH2 (Disulfide bridge:Cys2-Pen7) |
| Shortening | FCYW{Orn}T{Pen}T-NH2 (Disulfide bridge:Cys2-Pen7) |
| Formula | C50H67N11O11S2 |
| Molar Mass | 1062.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |