CSNK1-IN-2_product_DataBase

Bioactivity	CSNK1-IN-2 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 2.52 μM. CSNK1-IN-2 can be used for the research of proliferative disorders[1].
Target	IC50: 2.52 μM (CSNK1A1 kinase)
Invitro	CSNK1-IN-2 (example 7) 对 CSNK1A1、CSNK1D 和 CSNK1A1 (高 ATP) 具有抑制活性，IC50 值分别为 2.52 μM、8.48 μM 和 107 μM[1]。CSNK1-IN-2 对野生型 EGFR 激酶具有抑制作用，其 IC50 值为 2.74 nM[1]。
Name	CSNK1-IN-2
CAS	2468783-76-6
Formula	C28H26FN5O2
Molar Mass	483.54
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Reference	[1]. Volker Schulze, et al. 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

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