PeptideDB

CSD-CH2(1,8)-NH2

CAS: F: C76H125N25O15S2 W: 1693.09

CSD-CH2(1,8)-NH2 is a selective and competitive KOR antagonist (Ki: 6.8 nM). CSD-CH2(1,8)-NH2 inhibits calcium mobilizat
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Bioactivity CSD-CH2(1,8)-NH2 is a selective and competitive KOR antagonist (Ki: 6.8 nM). CSD-CH2(1,8)-NH2 inhibits calcium mobilization in DRG neurons. CH2(1,8)-NH2 antagonizes the antinociceptive effect of U50,488. CSD-CH2(1,8)-NH2 can be used for research of neuropsychiatric disorders[1].
Target Ki: 6.8 nM (KOR)
Name CSD-CH2(1,8)-NH2
Formula C76H125N25O15S2
Molar Mass 1693.09
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Muratspahić E, et al. Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples. J Med Chem. 2023 Sep 14;66(17):11843-11854.