| Bioactivity | CRF(6-33)(human) is a CRF binding protein (CRF-BP) ligand inhibitor. CRF(6-33)(human) competitively binds the CRF-BP but not the post-synaptic CRF receptors. CRF(6-33)(human) has anti-obesity effect[1][2]. | ||||||
| Name | CRF(6-33)(human) | ||||||
| CAS | 120066-38-8 | ||||||
| Shortening | ISLDLTFHLLREVLEMARAEQLAQQAHS | ||||||
| Formula | C141H231N41O43S | ||||||
| Molar Mass | 3220.66 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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| Reference | [1]. S C Heinrichs, et al. Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav Brain Res. 2001 Jul;122(1):43-50. [2]. S C Heinrichs, et al. Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol Behav. 2001 Sep 1-15;74(1-2):5-13. |