| Bioactivity | CPP12 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP12 can be used for intracellular delivery of therapeutic agents and chemical probes[1]. |
| Sequence | Cyclo(Phe-{d-Phe}-{2-Nal}-Arg-{d-Arg}-Arg-{d-Arg}-Gln) |
| Shortening | Cyclo(F-{d-Phe}-{2-Nal}-R-{d-Arg}-R-{d-Arg}-Q) |
| Formula | C60H85N21O9 |
| Molar Mass | 1244.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qian Z, et al. Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides. Biochemistry. 2016 May 10;55(18):2601-12. |