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CPCCOEt

CAS: 179067-99-3 F: C13H13NO4 W: 247.25

CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist ofmetabotropic glutamate receptor 1b (mG
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Bioactivity CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b)[1][2].
Name CPCCOEt
CAS 179067-99-3
Formula C13H13NO4
Molar Mass 247.25
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Litschig S, et al. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding. Mol Pharmacol. 1999 Mar;55(3):453-61.  [2]. Hermans E,et al. Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1alpha metabotropic glutamate receptor. Neuropharmacology. 1998 Dec;37(12):1645-7.