| Bioactivity | CP61, a cyclic peptide, is a dual CtBP1/CtBP2 inhibitor. CP61 binds CtBP1 with 3 μM affinity. CP61 inhibits the heterodimerization and homodimerization of CtBP2 with an IC50 value of 19 μM. CP61 is promising for research of cancers[1]. |
| CAS | 1631984-43-4 |
| Sequence | cyclo(Ser-Gly-Trp-Thr-Val-Val-Arg-Met-Tyr) |
| Shortening | cyclo(SGWTVVRMY) |
| Formula | C50H73N13O12S |
| Molar Mass | 1080.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Birts CN, et al. A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells. Chem Sci. 2013 Aug 1;4(8):3046-3057. |