| Bioactivity | Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25 μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities. |
| Target | Top I |
| CAS | 114457-62-4 |
| Formula | C14H18N2O4 |
| Molar Mass | 278.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Quantitation of 4-cyclohexyl-2-hydroxy-3-(3-methylsulfanyl-2-{2- [(morpholine-4-carbonyl)amino]-3- phenylpropionylamino}propionylamino)butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[(morpholine-4-carbonyl)amino]-3-phenylpropionic acid (CP-84,364) in dog and human plasma by high-performance liquid chromatography |