| Bioactivity | CP-319340 free base is a microsomal triglyceride transfer protein (MTP) inhibitor. |
| Target | MTP |
| Invitro | Microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) are necessary for lipoprotein assembly. MTP binds to ApoB with high affinity involving ionic interactions. MTP interacts at multiple sites in the N-terminal beta alpha structural domain of apoB[3]. |
| Name | CP-319340(free base) |
| CAS | 186390-35-2 |
| Formula | C27H23F3N4O |
| Molar Mass | 476.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sugi, Kiyoshi, et al. Process for producing 4-(2-methylphenyl)benzotrifluoride. EP1700837A1. [2]. Ye, Jin, et al. Treating hepatitis C virus infection. US20080175864A1. [3]. Hussain MM, et al. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res. 2003 Jan;44(1):22-32. |