| Bioactivity | CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress[1]. |
| Invitro | CP-312（10 µM；2 小时）在保护 hiPSC-CM 免受急性过氧化物诱导的细胞死亡方面表现出良好的效力，EC50 = 6.7 µM[1]。 |
| Name | CP-312 |
| CAS | 895470-67-4 |
| Formula | C16H12ClN3OS2 |
| Molar Mass | 361.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kirby RJ, et, al. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. |
CP-312
CAS: 895470-67-4 F: C16H12ClN3OS2 W: 361.87
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant resp
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