Bioactivity | CP-113818 is a potent cholesterol acyltransferase (ACAT) inhibitor. CP-113818 can be used for the research of Alzheimer's disease[1]. |
Invitro | CP-113818 inhibits Aβ production in cell-based experiments[1]. |
In Vivo | CP-113818 (0-7.1 mg/kg/day) markedly reduces amyloid pathology in a mouse model of Alzheimer's disease[1]. Animal Model: |
Name | CP-113818 |
CAS | 135025-12-6 |
Formula | C24H42N2OS3 |
Molar Mass | 470.80 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hutter-Paier B, et al. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron. 2004 Oct 14;44(2):227-38. |