Bioactivity | COX-2/15-LOX-IN-2 is a potent dual COX-2 and 15-LOX inhibitor with IC50 values of 0.065?μM and 1.86?μM, respectively. COX-2/15-LOX-IN-2 has potent antioxidant activity[1]. |
Name | COX-2/15-LOX-IN-2 |
Formula | C27H26N6OS2 |
Molar Mass | 514.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sara Elsayed, et al. Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity . Eur J Med Chem. 2023 Nov 15;260:115724. |