| Bioactivity | COX-2-IN-46 (compound 5m) is an anti-inflammatory agent with potent analgesic activity. COX-2-IN-46 exhibits a significant inhibitory effect on COX-2 (IC50=87.74 nM)[1]. |
| Formula | C28H19F2N3S |
| Molar Mass | 467.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mohammed, et al. "Discovery of new 2-(3-(naphthalen-2-yl)-4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024): 107372. |