Bioactivity | COX-2-IN-43 (Compound MYM4) is a COX-2 inhibitor (IC50: 0.983 and 0.247 μM for COX-1 and COX-2 respectively). COX-2-IN-43 inhibits cancer cell proliferation and colonization, induces apoptosis[1]. |
Invitro | COX-2-IN-43 抑制 CaCo-2, Hep3B, and HeLa 癌细胞的增殖, IC50 分别为 10.22, 4.84, and 1.57 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> COX-2-IN-43 相关抗体: |
CAS | 1023524-40-4 |
Formula | C18H11Cl2F3N2O3 |
Molar Mass | 431.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hawash M, et al. Exploration of isoxazole analogs: Synthesis, COX inhibition, anticancer screening, 3D multicellular tumor spheroids, and molecular modeling. Eur J Med Chem. 2024 Apr 15;271:116397. |