PeptideDB

COX-2-IN-42

CAS: F: C30H25N5O5S W: 567.62

COX-2-IN-42 (Compound T1) is a COX-2 inhibitor, and protects zebrafish against PTZ-induced neuronal damage.
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Bioactivity COX-2-IN-42 (Compound T1) is a COX-2 inhibitor, and protects zebrafish against PTZ-induced neuronal damage[1].
In Vivo 在斑马鱼模型中,COX-2-IN-42 (50-150 μM,腹腔注射) 可保护斑马鱼免受戊四唑 (PTZ) 诱导的神经元损伤和癫痫样病症[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
Formula C30H25N5O5S
Molar Mass 567.62
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Murugan R, et al. Neuroprotective potential of pyrazole benzenesulfonamide derivative T1 in targeted intervention against PTZ-induced epilepsy-like condition in in vivo zebrafish model. Int Immunopharmacol. 2024 Mar 15;131:111859.