Bioactivity | COX-2-IN-42 (Compound T1) is a COX-2 inhibitor, and protects zebrafish against PTZ-induced neuronal damage[1]. |
In Vivo | 在斑马鱼模型中,COX-2-IN-42 (50-150 μM,腹腔注射) 可保护斑马鱼免受戊四唑 (PTZ) 诱导的神经元损伤和癫痫样病症[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
Formula | C30H25N5O5S |
Molar Mass | 567.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Murugan R, et al. Neuroprotective potential of pyrazole benzenesulfonamide derivative T1 in targeted intervention against PTZ-induced epilepsy-like condition in in vivo zebrafish model. Int Immunopharmacol. 2024 Mar 15;131:111859. |