| Bioactivity | COX-2-IN-28 is a potent and selective COX-2 inhibitor with IC50 values of 0.054, 2.14, 13.21 µM for COX-2, 15-LOX, COX-1,respectively[1]. |
| Invitro | COX-2-IN-28 (compound 15c) shows significant COX-2 selectivity with an SI value of 244.63[1]. |
| Name | COX-2-IN-28 |
| CAS | 2413565-18-9 |
| Formula | C30H27N7S3 |
| Molar Mass | 581.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Maghraby MT, et al. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes. Bioorg Med Chem. 2020 Apr 1;28(7):115403. |
COX-2-IN-28
CAS: 2413565-18-9 F: C30H27N7S3 W: 581.78
COX-2-IN-28 is a potent and selective COX-2 inhibitor with IC50 values of 0.054, 2.14, 13.21 µM for COX-2, 15-LOX, COX-
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