| Bioactivity | COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1]. |
| Name | COX-1/2-IN-1 |
| CAS | 2358849-47-3 |
| Formula | C15H10BrClN2O |
| Molar Mass | 349.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Malose J. Mphahlele, et al. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides. Medicinal Chemistry Research volume 31, pages146–164 (2022) |
COX-1/2-IN-1
CAS: 2358849-47-3 F: C15H10BrClN2O W: 349.61
COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 i
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