| Bioactivity | COR627 is a GABA receptor positive allosteric modulator with the ability to enhance GABA activity. COR627 exhibits effects on GABA and baclofen stimulation in rat cortical membranes and can increase its affinity for GABA(B) receptors. In vivo experiments have shown that COR627 can enhance the sedative/hypnotic effects of baclofen at pretreatment ineffective doses[1]. |
| CAS | 329221-34-3 |
| Formula | C20H27NO3S |
| Molar Mass | 361.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor |