| Bioactivity | COQ7-IN-2 (compound 12) is an inhibitor of COQ7, witn IC50 values of 7.3 μM and 15.4 μM for DMQ10 and UQ10 accumulation, respectively[1]. | ||||||||||||
| Invitro | COQ7-IN-2 (compound 12) has less growth inhibition against human normal culture cells[1].The substantial DMQ10 accumulation occurred in both PANC-1 cells (8.7% by COQ7-IN-2 (compound 12)) and PC3 cells (14.0% by COQ7-IN-2 (compound 12))[1]. | ||||||||||||
| Name | COQ7-IN-2 | ||||||||||||
| CAS | 2579696-76-5 | ||||||||||||
| Formula | C15H13N3O | ||||||||||||
| Molar Mass | 251.28 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Keiko Tsuganezawa, et al. Identification of small molecule inhibitors of human COQ7. Bioorg Med Chem. 2020 Jan 1;28(1):115182. |