| Bioactivity | COMT-IN-2 (compund 9) is the potent COMT inhibitor, showing selective inhibition of brain (IC50=24 nM) and liver (IC50=81 nM) MB-COMT compared to the liver S-COMT (IC50=620 nM) isoform[1]. |
| Target | COMT |
| Formula | C13H13NO2 |
| Molar Mass | 215.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01682 |