Bioactivity | CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1]. | ||||||
Invitro | CMD178 TFA (100 μM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].CMD178 TFA (100 μM) inhibits the development of Treg cells induced by IL2/sIL-2Rα signaling[1]. | ||||||
Name | CMD178 TFA | ||||||
Formula | C9H8F5KO3Y | ||||||
Molar Mass | 964.05 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |