| Bioactivity | CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1]. |
| Name | CMB-087229 |
| CAS | 1227692-67-2 |
| Formula | C10H8Cl2N2O2 |
| Molar Mass | 259.09 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527. |
CMB-087229
CAS: 1227692-67-2 F: C10H8Cl2N2O2 W: 259.09
CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used
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