| Bioactivity | CM572 is a selective irreversible partial sigma-2 receptor agonist. CM572 has antitumor activity. CM572 induces dose-dependent cell death, with an EC50 of 7.6 μM in SK-N-SH neuroblastoma cells. CM572 can be used for the research of kinds of diseases such as neuroblastoma, breast cancer[1]. |
| Target | EC50: 7.6 μM (SK-N-SH neuroblastoma cells). |
| Name | CM572 |
| CAS | 1121932-91-9 |
| Formula | C22H23FN4O2S |
| Molar Mass | 426.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nicholson H, et al. Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity. J Pharmacol Exp Ther. 2015 Aug;354(2):203-12. |