| Bioactivity | CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer. |
| CAS | 1801552-75-9 |
| Sequence | Cys-Leu-Lys-Ala-Asp-Lys-Ala-Lys-Cys (disulfide bridge:Cys1-Cys9) |
| Shortening | CLKADKAKC (disulfide bridge:Cys1-Cys9) |
| Formula | C40H72N12O12S2 |
| Molar Mass | 977.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng GK, et al. SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide. J Control Release. 2014 Oct 28;192:236-42. |