Bioactivity | CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer. |
CAS | 1801552-75-9 |
Sequence | Cys-Leu-Lys-Ala-Asp-Lys-Ala-Lys-Cys (disulfide bridge:Cys1-Cys9) |
Shortening | CLKADKAKC (disulfide bridge:Cys1-Cys9) |
Formula | C40H72N12O12S2 |
Molar Mass | 977.20 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Feng GK, et al. SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide. J Control Release. 2014 Oct 28;192:236-42. |