| Bioactivity | CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 µM for CK-1δ[1][2]. |
| In Vivo | CK1-IN-3 (compound 35) (100 nM; feed) 显著延长果蝇寿命至36.17天[2]。 |
| Name | CK1-IN-3 |
| CAS | 349438-74-0 |
| Formula | C17H16N2O3S |
| Molar Mass | 328.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ana MARTÍNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1. [2]. Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57(6):2755-72. |