| Bioactivity | CK-548 (CK-0993548) is a Arp2/3 complex inhibitor with the IC50 of 11 μM. CK-548 inhibits HIV-1 nuclear migration and infection[1][2]. |
| CAS | 388604-55-5 |
| Formula | C15H11BrClNO2S |
| Molar Mass | 384.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. B. J. Nolen, et al. Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature. [2]. Spear M, et al. HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration. J Biol Chem. 2014;289(10):6949-6959. |
CK-548
CAS: 388604-55-5 F: C15H11BrClNO2S W: 384.68
CK-548 (CK-0993548) is a Arp2/3 complex inhibitor with the IC50 of 11 μM. CK-548 inhibits HIV-1 nuclear migration and i
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