| Bioactivity | CK-3197 is a weaker inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase(CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure. The positive inotropy with CK-3197 is associated with small increases in heart rate (HR) without adverse effects on CBF[1]. |
| CAS | 132523-92-3 |
| Formula | C23H22N4O3 |
| Molar Mass | 402.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Greenberg S, et al. Hemodynamic and myocardial energetic effects of CK-3197, a selective positive inotropic agent. J Cardiovasc Pharmacol. 1991 Jan;17(1):145-53. |