| Bioactivity | CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria[1]. |
| Target | IC50: 15 µg/mL (SecA) |
| Invitro | CJ-21,058 (0-20 µg/mL) 显示出抗菌活性，对 Staphylococcus aureus 01A1105，Streptococcus pyogenes 02C1068，Enterococcus faecalis 03A1069，Escherichia coli 51A0266 的 MIC 值分别为 5、>20、5、>20 µg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> CJ-21,058 相关抗体: |
| CAS | 405072-57-3 |
| Formula | C23H33NO4 |
| Molar Mass | 387.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sugie Y, et al. CJ-21,058, a new SecA inhibitor isolated from a fungus. J Antibiot (Tokyo). 2002 Jan;55(1):25-9. |