| Bioactivity | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. | ||||||||||||
| Target | GPR 27. | ||||||||||||
| Invitro | CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1]. | ||||||||||||
| Name | CID 1375606 | ||||||||||||
| CAS | 313493-80-0 | ||||||||||||
| Formula | C20H14Cl2N2O2 | ||||||||||||
| Molar Mass | 385.24 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608. |