| Bioactivity | CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism[1]. |
| CAS | 1253919-92-4 |
| Formula | C26H39N5O4S |
| Molar Mass | 517.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nishimura Y, et al., Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism. J Med Chem. 2018 Jul 26;61(14):5949-5962. |
CH5447240
CAS: 1253919-92-4 F: C26H39N5O4S W: 517.68
CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.