| Bioactivity | CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM[1]. | ||||||
| Name | CH 5450 | ||||||
| CAS | 252557-97-4 | ||||||
| Sequence | Z-Ile-Glu-Pro-Phe-Ome | ||||||
| Shortening | ZIEPF-Ome | ||||||
| Formula | C34H44N4O9 | ||||||
| Molar Mass | 652.73 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
CH 5450
CAS: 252557-97-4 F: C34H44N4O9 W: 652.73
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the actio
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