| Bioactivity | CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A can be used for study of arthritis[1]. |
| In Vivo | CGS 27023A (75 µmol/kg，灌胃10 h) 对溶基质素诱导的兔软骨降解模型有抑制作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 169799-04-6 |
| Formula | C18H24ClN3O5S |
| Molar Mass | 429.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. MacPherson LJ, et al. Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. J Med Chem. 1997;40(16):2525-2532. |
CGS 27023A
CAS: 169799-04-6 F: C18H24ClN3O5S W: 429.92
CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1,
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.