| Bioactivity | CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively. |
| Target | IC50: 57 nM (CGRP receptor)Ki: 35 nM(CGRP receptor) |
| Invitro | CGRP antagonist 1 is compound 20[1]. |
| Name | CGRP antagonist 1 |
| CAS | 1123757-49-2 |
| Formula | C29H26N4O4 |
| Molar Mass | 494.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Stump CA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett. 2009 Jan 1;19(1):214-7. |