| Bioactivity | CGP36216 (Compound 9) is a GABAB receptor antagonist. CGP36216 binds to GABAB receptor with a Ki value of 0.3 μM. CGP36216 can be used for research of anxiety and trauma-related disorders[1][2]. |
| Target | GABAB receptor |
| Name | CGP36216 |
| CAS | 123691-29-2 |
| Formula | C5H14NO2P |
| Molar Mass | 151.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. William Howson, et al. Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity. Bioorganic & Medicinal Chemistry Letters. Volume 3, Issue 4, April 1993, Pages 515-518. [2]. Adkins JM, et al. Presynaptic GABAB receptor inhibition sex dependently enhances fear extinction and attenuates fear renewal. Psychopharmacology (Berl). 2021 Aug;238(8):2059-2071. |