| Bioactivity | CFTR corrector 15 (Compound 4172) is a corrector for cystic fibrosis transmembrane conductance regulator (CFTR), that repairs the F508del-CFTR folding defect, especially used with VX-809 (HY-13262). CFTR corrector 15 can be used in research of cystic fibrosis disease[1]. |
| CAS | 1170387-92-4 |
| Formula | C24H22ClN5O2S |
| Molar Mass | 479.98 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Vaccarin C, et al., Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). J Med Chem. 2024 Aug 22;67(16):13891-13908. |
CFTR corrector 15
CAS: 1170387-92-4 F: C24H22ClN5O2S W: 479.98
CFTR corrector 15 (Compound 4172) is a corrector for cystic fibrosis transmembrane conductance regulator (CFTR), that re
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.