| Bioactivity | CFM-5 inhibits CARP-1/CCAR1-APC-2 interaction with an IC50 value of 0.75 μM. CFM-5 inhibits medulloblastoma (MB) cell proliferation and induces apoptosis[1][2]. |
| CAS | 639507-03-2 |
| Formula | C23H18BrN3OS |
| Molar Mass | 464.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abdelkader E Ashour, et al. CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth. PLoS One. 2013 Jun 24;8(6):e66733. [2]. Magesh Muthu, et al. CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis. Oncotarget. 2015 Mar 30;6(9):6499-510. |