CDK8-IN-5_product_DataBase

CAS: 2855087-10-2 F: C26H22N2O4 W: 426.46

CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease[1].
Name	CDK8-IN-5
CAS	2855087-10-2
Formula	C26H22N2O4
Molar Mass	426.46
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Yan Y, et al. Discovery and Anti-Inflammatory Activity Evaluation of a Novel CDK8 Inhibitor through Upregulation of IL-10 for the Treatment of Inflammatory Bowel Disease In Vivo. J Med Chem. 2022 May 26;65(10):7334-7362.

PeptideDB