Bioactivity | CDK4/6-IN-20 (Compound II-5) is a CDK4/CDK6 inhibitor with IC50 values of 1.9, 14.2 nM, respectively. CDK4/6-IN-20 also inhibits cell proliferation and can be used in cancer research[1]. |
Invitro | CDK4/6-IN-20 抑制 MCF7 和 T47D 细胞的增殖,IC50 值分别为 169 和 92 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> CDK4/6-IN-20 相关抗体: |
CAS | 3033950-84-1 |
Formula | C23H24FN5O2 |
Molar Mass | 421.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. HU, Pu, et al. 2-aminopyrimidine compound, and use and pharmaceutical composition thereof.WO2024066986A1. |