| Bioactivity | CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells[1]. |
| Target | IC50: 117.6 nM (CDK2) |
| Name | CDK2/Bcl2-IN-1 |
| Formula | C35H56O10S |
| Molar Mass | 668.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eltamany EE, et al. A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition. ACS Omega. 2023 Aug 8;8(33):30630-30639. |