| Bioactivity | CDK2-IN-9 is a potent CDK2 inhibitor with an IC50 of 0.63 µM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma[1]. |
| Invitro | CDK2-IN-9 (compound 5c) shows antiproliferative activity with IC50s of 3.03, 8.62, 62.52 µM for MDA-MB-435, SNB-75, WI-38 cells, respectively[1].CDK2-IN-9 (24 h) induces apoptosis and cell cycle arrest in S and G2/M phase[1]. Apoptosis Analysis[1] Cell Line: |
| Name | CDK2-IN-9 |
| Formula | C21H16ClN3O4S |
| Molar Mass | 441.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |