Bioactivity | CDK2-IN-19 (Compound 32) is a selective and orally active CDK2 inhibitor (Ki: 0.18 nM). CDK2-IN-19 shows anticancer activity in mice bearing OVCAR3 tumors[1]. |
Target | Ki: 0.18 nM (CDK2) |
Name | CDK2-IN-19 |
Formula | C20H21FN6O4S |
Molar Mass | 460.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mingshuo Zeng, et al. Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2). ACS Med. Chem. Lett. 2023. |