| Bioactivity | CDDO-3P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-3P-Im can reduce the size and the severity of the lung tumors in mouse lung cancer model[1]. CDDO-3P-Im is a orally active necroptosis inhibitor that can be used for the research of ischemia/reperfusion (I/R)[2]. | ||||||||||||
| Invitro | CDDO-3P-Im (30-100 nM; 4 days) induces differentiation of U937 cells at 30 nM[1].CDDO-3P-Im suppresses NO production in RAW264.7 cells with an IC50 of 4.3 nM[1]. Apoptosis Analysis[1] Cell Line: | ||||||||||||
| Name | CDDO-3P-Im | ||||||||||||
| CAS | 1883650-95-0 | ||||||||||||
| Formula | C39H46N4O3 | ||||||||||||
| Molar Mass | 618.81 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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