PeptideDB

CDDO-3P-Im

CAS: 1883650-95-0 F: C39H46N4O3 W: 618.81

CDDO-3P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-3P-Im can reduce the size and the severi
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity CDDO-3P-Im is an analogue of CDDO-Imidazolide with chemopreventive effect. CDDO-3P-Im can reduce the size and the severity of the lung tumors in mouse lung cancer model[1]. CDDO-3P-Im is a orally active necroptosis inhibitor that can be used for the research of ischemia/reperfusion (I/R)[2].
Invitro CDDO-3P-Im (30-100 nM; 4 days) induces differentiation of U937 cells at 30 nM[1].CDDO-3P-Im suppresses NO production in RAW264.7 cells with an IC50 of 4.3 nM[1]. Apoptosis Analysis[1] Cell Line:
Name CDDO-3P-Im
CAS 1883650-95-0
Formula C39H46N4O3
Molar Mass 618.81
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month