Bioactivity | CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell[1]. |
Name | CD24/Siglec-10 blocking peptide, CSBP |
Sequence | {d-Leu}-{d-Asp}-{d-Val}-{d-Phe}-{d-Leu}-{d-Tyr}-{d-Ser}-{d-Glu} |
Shortening | {d-Leu}-{d-Asp}-{d-Val}-{d-Phe}-{d-Leu}-{d-Tyr}-{d-Ser}-{d-Glu} |
Formula | C47H68N8O15 |
Molar Mass | 985.09 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wenhui Shen, et al. Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy. J Immunother Cancer. 2023 Jun;11(6):e007068. |