| Bioactivity | CCX354 is an antagonist of CCR1, with anti-inflammatory activity. | ||||||||||||
| Invitro | CCX354 shows potent activities in the chemotaxis assay, with IC50 < 100 nM[1]. | ||||||||||||
| In Vivo | In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1]. | ||||||||||||
| Name | CCX354 | ||||||||||||
| CAS | 1010073-75-2 | ||||||||||||
| Formula | C22H22ClN7O2 | ||||||||||||
| Molar Mass | 451.91 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1 |